TY - GEN
T1 - CFD analysis incorporating the influence of wall motion
T2 - 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006
AU - Dempere-Marco, Laura
AU - Oubel, Estanislao
AU - Castro, Marcelo
AU - Putman, Christopher
AU - Frangi, Alejandro
AU - Cebral, Juan
PY - 2006
Y1 - 2006
N2 - Haemodynamics, and in particular wall shear stress, is thought to play a critical role in the progression and rupture of intracranial aneurysms. A novel method is presented that combines image-based wall motion estimation obtained through non-rigid registration with computational fluid dynamics (CFD) simulations in order to provide realistic intra-aneurysmal flow patterns and understand the effects of deforming walls on the haemodynamic patterns. In contrast to previous approaches, which assume rigid walls or ad hoc elastic parameters to perform the CFD simulations, wall compliance has been included in this study through the imposition of measured wall motions. This circumvents the difficulties in estimating personalized elasticity properties. Although variations in the aneurysmal haemodynamics were observed when incorporating the wall motion, the overall characteristics of the wall shear stress distribution do not seem to change considerably. Further experiments with more cases will be required to establish the clinical significance of the observed variations.
AB - Haemodynamics, and in particular wall shear stress, is thought to play a critical role in the progression and rupture of intracranial aneurysms. A novel method is presented that combines image-based wall motion estimation obtained through non-rigid registration with computational fluid dynamics (CFD) simulations in order to provide realistic intra-aneurysmal flow patterns and understand the effects of deforming walls on the haemodynamic patterns. In contrast to previous approaches, which assume rigid walls or ad hoc elastic parameters to perform the CFD simulations, wall compliance has been included in this study through the imposition of measured wall motions. This circumvents the difficulties in estimating personalized elasticity properties. Although variations in the aneurysmal haemodynamics were observed when incorporating the wall motion, the overall characteristics of the wall shear stress distribution do not seem to change considerably. Further experiments with more cases will be required to establish the clinical significance of the observed variations.
UR - http://www.scopus.com/inward/record.url?scp=79551685377&partnerID=8YFLogxK
U2 - 10.1007/11866763_54
DO - 10.1007/11866763_54
M3 - Conference contribution
C2 - 17354802
AN - SCOPUS:79551685377
SN - 354044727X
SN - 9783540447276
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 438
EP - 445
BT - Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006
PB - Springer-Verlag Italia
Y2 - 1 October 2006 through 6 October 2006
ER -