CFTR three-dimensional structure.

Robert C. Ford, James Birtley, Mark F. Rosenberg, Liang Zhang

    Research output: Contribution to journalArticlepeer-review


    CFTR is a member of the ATP-binding cassette family of membrane proteins. This is one of the best characterised membrane protein families in terms of structure and function. CFTR operates as an ion channel, unlike nearly all other family members which are active transporters. Here, we discuss methods that have allowed such data to be obtained for CFTR.
    Original languageEnglish
    Pages (from-to)329-346
    Number of pages17
    JournalMethods in Molecular Biology
    Publication statusPublished - 2011


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