C–H Borylation: No Need to Stop for Directions

Hugh C. Osborne; Alastair Durie; Christine K. Schmidt; Igor Larrosa

doi:10.1016/j.trechm.2020.07.009

C–H Borylation: No Need to Stop for Directions

Hugh C. Osborne, Alastair Durie, Christine K. Schmidt, Igor Larrosa

Research output: Contribution to journal › Article › peer-review

140 Downloads (Pure)

Abstract

A recent work by Hartwig et al. (Science, 2020) details an efficient method to borylate strong primary C(sp3)–H bonds via iridium-catalysed C–H activation. The conditions confer counterintuitive selectivity over more labile C–H bonds, while providing an avenue for a gamut of synthetically valuable late-stage functionalisations through versatile borylate intermediates.

Original language	English
Journal	Trends in Chemistry
Early online date	17 Aug 2020
DOIs	https://doi.org/10.1016/j.trechm.2020.07.009
Publication status	E-pub ahead of print - 17 Aug 2020

Access to Document

10.1016/j.trechm.2020.07.009

Trends - Spotlight - TitlesAccepted author manuscript, 418 KB

https://linkinghub.elsevier.com/retrieve/pii/S2589597420301799

Cite this

@article{ded34e8c90cc4466ae7a7b7a55695ebf,

title = "C–H Borylation: No Need to Stop for Directions",

abstract = "A recent work by Hartwig et al. (Science, 2020) details an efficient method to borylate strong primary C(sp3)–H bonds via iridium-catalysed C–H activation. The conditions confer counterintuitive selectivity over more labile C–H bonds, while providing an avenue for a gamut of synthetically valuable late-stage functionalisations through versatile borylate intermediates.",

author = "Osborne, {Hugh C.} and Alastair Durie and Schmidt, {Christine K.} and Igor Larrosa",

year = "2020",

month = aug,

day = "17",

doi = "10.1016/j.trechm.2020.07.009",

language = "English",

journal = "Trends in Chemistry",

issn = "2589-5974",

publisher = "Cell Press",

}

TY - JOUR

T1 - C–H Borylation: No Need to Stop for Directions

AU - Osborne, Hugh C.

AU - Durie, Alastair

AU - Schmidt, Christine K.

AU - Larrosa, Igor

PY - 2020/8/17

Y1 - 2020/8/17

N2 - A recent work by Hartwig et al. (Science, 2020) details an efficient method to borylate strong primary C(sp3)–H bonds via iridium-catalysed C–H activation. The conditions confer counterintuitive selectivity over more labile C–H bonds, while providing an avenue for a gamut of synthetically valuable late-stage functionalisations through versatile borylate intermediates.

AB - A recent work by Hartwig et al. (Science, 2020) details an efficient method to borylate strong primary C(sp3)–H bonds via iridium-catalysed C–H activation. The conditions confer counterintuitive selectivity over more labile C–H bonds, while providing an avenue for a gamut of synthetically valuable late-stage functionalisations through versatile borylate intermediates.

U2 - 10.1016/j.trechm.2020.07.009

DO - 10.1016/j.trechm.2020.07.009

M3 - Article

SN - 2589-5974

JO - Trends in Chemistry

JF - Trends in Chemistry

ER -

C–H Borylation: No Need to Stop for Directions

Abstract

Access to Document

Fingerprint

Cite this