Abstract
Treatment of rats with triiodothyronine (T3 10 μg/100 g per day, 20 days) increased the mass of brown adipose tissue (BAT) and heart ventricle and stimulated β-adrenoreceptor number (assessed from radioligand binding) by 43% in isolated BAT and heart membranes. α-Receptors number was slightly increased in BAT membranes (42%) but reduced in heart from T3-treated rats. The ratio of α-receptors/β-receptors was unaffected by T3 treatment in BAT membranes (control and hyperthyroid = 1.54) but reduced in heart (control = 2.8, T3 = 1.04). © 1985.
Original language | English |
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Pages (from-to) | 227-229 |
Number of pages | 2 |
Journal | European journal of pharmacology |
Volume | 114 |
Issue number | 2 |
Publication status | Published - 15 Aug 1985 |
Keywords
- α-Adrenoreceptors
- β-Adrenoceptors
- Brown adipose tissue
- Heart
- Triiodothyronine