Changes in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy

Michelle N. Harvie; I. T. Campbell; N. Thatcher; A. Baildam

doi:10.1046/j.1365-277X.2003.00459.x

Changes in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy

Michelle N. Harvie, I. T. Campbell, N. Thatcher, A. Baildam

Research output: Contribution to journal › Article › peer-review

Abstract

Background. Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. Methods. Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. Results. Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 ± 5.5 to 27.9 ± 7.9% (P <0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 ± 15.9 to 105.1 ± 10.1% of the value predicted from the Harris Benedict equation (P <0.05). In the women resting energy expenditure (REE) did not alter. Conclusion. Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.

Original language	English
Pages (from-to)	323-326
Number of pages	3
Journal	Journal of Human Nutrition and Dietetics
Volume	16
Issue number	5
DOIs	https://doi.org/10.1046/j.1365-277X.2003.00459.x
Publication status	Published - Oct 2003

Keywords

Body composition
Dietary intake
Energy expenditure
Gender
Nonsmall cell lung cancer
Resting

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1046/j.1365-277X.2003.00459.x

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title = "Changes in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy",

abstract = "Background. Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. Methods. Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. Results. Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 ± 5.5 to 27.9 ± 7.9% (P <0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 ± 15.9 to 105.1 ± 10.1% of the value predicted from the Harris Benedict equation (P <0.05). In the women resting energy expenditure (REE) did not alter. Conclusion. Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.",

keywords = "Body composition, Dietary intake, Energy expenditure, Gender, Nonsmall cell lung cancer, Resting",

author = "Harvie, {Michelle N.} and Campbell, {I. T.} and N. Thatcher and A. Baildam",

year = "2003",

month = oct,

doi = "10.1046/j.1365-277X.2003.00459.x",

language = "English",

volume = "16",

pages = "323--326",

journal = "Journal of Human Nutrition and Dietetics",

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T1 - Changes in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy

AU - Harvie, Michelle N.

AU - Campbell, I. T.

AU - Thatcher, N.

AU - Baildam, A.

PY - 2003/10

Y1 - 2003/10

N2 - Background. Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. Methods. Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. Results. Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 ± 5.5 to 27.9 ± 7.9% (P <0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 ± 15.9 to 105.1 ± 10.1% of the value predicted from the Harris Benedict equation (P <0.05). In the women resting energy expenditure (REE) did not alter. Conclusion. Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.

AB - Background. Men with nonsmall cell lung cancer (NSCLC) are more susceptible to weight loss than women. The composition and aetiology of these gender specific weight changes are not known. Methods. Measurements of body mass, body composition and energy balance (resting energy expenditure and energy intake) were made in 15 men and six women before and after chemotherapy for NSCLC. Results. Over the course of chemotherapy minimal weight change was observed in both men and women. Men increased body fat from 25.0 ± 5.5 to 27.9 ± 7.9% (P <0.05) whereas fat free mass (FFM) tended to decrease (P = 0.063). There was no change in body fat or FFM in the women. In the men resting energy expenditure decreased over the course of chemotherapy from 113.2 ± 15.9 to 105.1 ± 10.1% of the value predicted from the Harris Benedict equation (P <0.05). In the women resting energy expenditure (REE) did not alter. Conclusion. Over the course of chemotherapy for NSCLC, men and women appear to have different patterns of change in body composition and in energy expenditure.

KW - Body composition

KW - Dietary intake

KW - Energy expenditure

KW - Gender

KW - Nonsmall cell lung cancer

KW - Resting

U2 - 10.1046/j.1365-277X.2003.00459.x

DO - 10.1046/j.1365-277X.2003.00459.x

M3 - Article

SN - 0952-3871

VL - 16

SP - 323

EP - 326

JO - Journal of Human Nutrition and Dietetics

JF - Journal of Human Nutrition and Dietetics

IS - 5

ER -

Changes in body composition in men and women with advanced nonsmall cell lung cancer (NSCLC) undergoing chemotherapy

Abstract

Keywords

UN SDGs

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