Changes in potassium currents of vascular smooth muscle cells from hindquarter arteries of 4-wk simulated weightless rats

Z.-J. Fu; H.-W. Cheng; L.-F. Zhang; J. Ma

Changes in potassium currents of vascular smooth muscle cells from hindquarter arteries of 4-wk simulated weightless rats

Z.-J. Fu, H.-W. Cheng, L.-F. Zhang, J. Ma

Division of Cardiovascular Sciences (L5)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

It was recognized that multiple mechanisms were responsible for postflight cardiovascular dysfunction on returning to the 1-g environment. Thus, the peripheral resistance play an important role in maintaining and regulating the blood pressure, more and more attention was focused on adaptational changes of small arteries after real/simulated weightlessness. It was found that the BKCa current densities and the KV current densities of VSMCs from SUS group were significantly greater than those of CON group, these changes hyperpolarized the VSMCs from SUS group.

Original language	Undefined
Title of host publication	European Space Agency, (Special Publication) ESA SP
Pages	209-210
Number of pages	1
Publication status	Published - 2002

Keywords

Head-down tilt
Space Flight
Weightlessness

Cite this

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title = "Changes in potassium currents of vascular smooth muscle cells from hindquarter arteries of 4-wk simulated weightless rats",

abstract = "It was recognized that multiple mechanisms were responsible for postflight cardiovascular dysfunction on returning to the 1-g environment. Thus, the peripheral resistance play an important role in maintaining and regulating the blood pressure, more and more attention was focused on adaptational changes of small arteries after real/simulated weightlessness. It was found that the BKCa current densities and the KV current densities of VSMCs from SUS group were significantly greater than those of CON group, these changes hyperpolarized the VSMCs from SUS group.",

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author = "Z.-J. Fu and H.-W. Cheng and L.-F. Zhang and J. Ma",

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AU - Fu, Z.-J.

AU - Cheng, H.-W.

AU - Zhang, L.-F.

AU - Ma, J.

PY - 2002

Y1 - 2002

N2 - It was recognized that multiple mechanisms were responsible for postflight cardiovascular dysfunction on returning to the 1-g environment. Thus, the peripheral resistance play an important role in maintaining and regulating the blood pressure, more and more attention was focused on adaptational changes of small arteries after real/simulated weightlessness. It was found that the BKCa current densities and the KV current densities of VSMCs from SUS group were significantly greater than those of CON group, these changes hyperpolarized the VSMCs from SUS group.

AB - It was recognized that multiple mechanisms were responsible for postflight cardiovascular dysfunction on returning to the 1-g environment. Thus, the peripheral resistance play an important role in maintaining and regulating the blood pressure, more and more attention was focused on adaptational changes of small arteries after real/simulated weightlessness. It was found that the BKCa current densities and the KV current densities of VSMCs from SUS group were significantly greater than those of CON group, these changes hyperpolarized the VSMCs from SUS group.

KW - Head-down tilt

KW - Space Flight

KW - Weightlessness

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-0036771137&partnerID=MN8TOARS

M3 - Conference contribution

SP - 209

EP - 210

BT - European Space Agency, (Special Publication) ESA SP

ER -

Changes in potassium currents of vascular smooth muscle cells from hindquarter arteries of 4-wk simulated weightless rats

Abstract

Keywords

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Cite this