Changes in refraction, ocular aberrations, and corneal structure after suspending rigid gas-permeable contact lens wear in Keratoconus

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    Purpose:: This study reports on changes in visual acuity, ocular higher-order aberrations, and refraction after suspending rigid gas-permeable lens wear for 1 week in 15 patients with moderate to severe keratoconus. Alterations in the anterior surface, central corneal powers and axes, and central corneal thickness were also explored. Methods:: Scheimpflug photography and Hartmann-Shack aberrometry were performed at 2 visits, 7 days apart, after the patients had removed their habitual contact lenses. Subjective refraction and both high- and low-contrast logarithm of the minimum angle of resolution visual acuities were also recorded at both visits. Results:: Reductions in both high-contrast visual acuity (P=0.001) and low-contrast visual acuity (P=0.002), along with an increase in third-order root mean square aberrations (P=0.008), occurred after rigid gas-permeable lens wear was suspended in these patients with keratoconus. However, no significant changes in subjective refraction were found over the 1-week period (P <0.10). Significant correlations were observed between third-order coma root mean square aberrations and the measured high-contrast (rp <0.59; P ≤ 0.02) and low-contrast visual acuities (rP <0.61; P ≤ 0.015). In addition to increases in the anterior surface central corneal powers (P ≤ 0.02), a reduction in central corneal thickness also was found between the 2 visits (P=0.00016). Conclusions:: Changes in the optical and structural parameters of the keratoconic cornea occur after suspending rigid gas-permeable contact lens wear. This information may be of interest to practitioners concerned with prescribing aberration-controlling soft contact lenses for such patients. © 2012 by Lippincott Williams & Wilkins.
    Original languageEnglish
    Pages (from-to)500-508
    Number of pages8
    Issue number5
    Publication statusPublished - May 2012


    • higher-order abberations
    • keratoconus
    • refraction
    • rigid gas-permeable contact lenses
    • visual activity


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