Changes in vascular endothelium related to lymphocyte collections in diseased synovia

A. J. Freemont; C. J P Jones; M. Bromley; P. Andrews

Changes in vascular endothelium related to lymphocyte collections in diseased synovia

A. J. Freemont, C. J P Jones, M. Bromley, P. Andrews

Research output: Contribution to journal › Article › peer-review

Abstract

A population of small blood vessels are described in the synovia of patients with a number of different arthropathies. These vessels are identical to the high endothelial venules (HEV) of lymph node paracortex, known to be the site of lymphocyte diapedesis from blood to tissues. The significance of this finding and its possible role in the pathogenesis of inflammatory arthritides are discussed.

Original language	English
Pages (from-to)	1427-1433
Number of pages	6
Journal	Arthritis Care & Research
Volume	26
Issue number	12
Publication status	Published - 1983

Keywords

pathology: Arthritis
pathology: Arthritis, Juvenile Rheumatoid
pathology: Arthritis, Rheumatoid
Cell Movement
pathology: Endothelium
Histocytochemistry
Humans
Hyperplasia
pathology: Lymphocytes
Microscopy, Electron
pathology: Reiter Disease
Research Support, Non-U.S. Gov't
blood supply: Synovial Membrane
pathology: Veins
pathology: Venules

Cite this

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title = "Changes in vascular endothelium related to lymphocyte collections in diseased synovia",

abstract = "A population of small blood vessels are described in the synovia of patients with a number of different arthropathies. These vessels are identical to the high endothelial venules (HEV) of lymph node paracortex, known to be the site of lymphocyte diapedesis from blood to tissues. The significance of this finding and its possible role in the pathogenesis of inflammatory arthritides are discussed.",

keywords = "pathology: Arthritis, pathology: Arthritis, Juvenile Rheumatoid, pathology: Arthritis, Rheumatoid, Cell Movement, pathology: Endothelium, Histocytochemistry, Humans, Hyperplasia, pathology: Lymphocytes, Microscopy, Electron, pathology: Reiter Disease, Research Support, Non-U.S. Gov't, blood supply: Synovial Membrane, pathology: Veins, pathology: Venules",

author = "Freemont, {A. J.} and Jones, {C. J P} and M. Bromley and P. Andrews",

year = "1983",

language = "English",

volume = "26",

pages = "1427--1433",

journal = "Arthritis Care & Research",

issn = "2151-464X",

publisher = "John Wiley & Sons Ltd",

number = "12",

}

TY - JOUR

T1 - Changes in vascular endothelium related to lymphocyte collections in diseased synovia

AU - Freemont, A. J.

AU - Jones, C. J P

AU - Bromley, M.

AU - Andrews, P.

PY - 1983

Y1 - 1983

N2 - A population of small blood vessels are described in the synovia of patients with a number of different arthropathies. These vessels are identical to the high endothelial venules (HEV) of lymph node paracortex, known to be the site of lymphocyte diapedesis from blood to tissues. The significance of this finding and its possible role in the pathogenesis of inflammatory arthritides are discussed.

AB - A population of small blood vessels are described in the synovia of patients with a number of different arthropathies. These vessels are identical to the high endothelial venules (HEV) of lymph node paracortex, known to be the site of lymphocyte diapedesis from blood to tissues. The significance of this finding and its possible role in the pathogenesis of inflammatory arthritides are discussed.

KW - pathology: Arthritis

KW - pathology: Arthritis, Juvenile Rheumatoid

KW - pathology: Arthritis, Rheumatoid

KW - Cell Movement

KW - pathology: Endothelium

KW - Histocytochemistry

KW - Humans

KW - Hyperplasia

KW - pathology: Lymphocytes

KW - Microscopy, Electron

KW - pathology: Reiter Disease

KW - Research Support, Non-U.S. Gov't

KW - blood supply: Synovial Membrane

KW - pathology: Veins

KW - pathology: Venules

M3 - Article

SN - 2151-464X

VL - 26

SP - 1427

EP - 1433

JO - Arthritis Care & Research

JF - Arthritis Care & Research

IS - 12

ER -

Changes in vascular endothelium related to lymphocyte collections in diseased synovia

Abstract

Keywords

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