Characterisation of breast implant surfaces and correlation with fibroblast adhesion

Introduction: Capsular contracture formation is a common complication following breast augmentation surgery. Breast implant shells have either a smooth or a textured surface. Smooth surfaces demonstrate a higher incidence of contracture formation. The 3-dimensional surface of textured implants is thought to disrupt contractile forces and reduce capsular contracture rates. Aim: To investigate the interaction of fibroblasts with silicone breast implant surfaces through characterization of their unique features. Method: Surfaces of smooth and textured breast implants were characterized using a confocal laser scanning microscope, a microtest 5. kN tensile testing device, and a contact angle goniometer. The kinetics of fibroblast interaction with these surfaces was further analysed. Results: The textured surfaces were rough, and nodular containing high peaks and deep crevasses with roughness (Sa) values in the range 8.88-18.83. μm and contact angles between 130° and 142°. The smooth implant surfaces were less rough, more regular and repetitive with 0.06-0.07. μm surface roughness, and contact angles between 110.9° and 111.8°. The textured surfaces displayed higher bending stiffness than the smooth surfaces (0.19 and 0.26. N. mm). Significant (p