Characterization of the novel HLA-DQB1*06:48 allele by group-specific sequencing

L. Foster, D. Tate, K Poulton

Research output: Contribution to journalArticlepeer-review


HLA-DQB1*06:48 has single nucleotide polymorphisms within codons 70 and 62 of exon 2 (GGG>AGG and AAG>AAC) relative to HLA-DQB1*06:02:01 and HLA-DQB1*06:37. This results in amino acid differences (G>R and K>N) that will change the polarity and charge of the encoded antigen and may therefore affect its peptide repertoire.

Original languageEnglish
Pages (from-to)322-3
Number of pages2
JournalInternational Journal of Immunogenetics
Issue number4
Publication statusPublished - Aug 2013


  • Alleles
  • Amino Acid Substitution
  • Asian Continental Ancestry Group
  • Base Sequence
  • Genetic Variation
  • HLA-DQ beta-Chains
  • Histocompatibility Testing
  • Humans
  • Male
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA
  • Journal Article


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