Abstract
HLA-DQB1*06:48 has single nucleotide polymorphisms within codons 70 and 62 of exon 2 (GGG>AGG and AAG>AAC) relative to HLA-DQB1*06:02:01 and HLA-DQB1*06:37. This results in amino acid differences (G>R and K>N) that will change the polarity and charge of the encoded antigen and may therefore affect its peptide repertoire.
| Original language | English |
|---|---|
| Pages (from-to) | 322-3 |
| Number of pages | 2 |
| Journal | International Journal of Immunogenetics |
| Volume | 40 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 2013 |
Keywords
- Alleles
- Amino Acid Substitution
- Asian Continental Ancestry Group
- Base Sequence
- Genetic Variation
- HLA-DQ beta-Chains
- Histocompatibility Testing
- Humans
- Male
- Polymorphism, Single Nucleotide
- Sequence Analysis, DNA
- Journal Article
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