Characterizing the elastic properties of tissues

Riaz Akhtar; Michael J. Sherratt; J. Kennedy Cruickshank; Brian Derby

doi:10.1016/S1369-7021(11)70059-1

Characterizing the elastic properties of tissues

Riaz Akhtar, Michael J. Sherratt, J. Kennedy Cruickshank, Brian Derby

Research output: Contribution to journal › Article › peer-review

Abstract

The quality of life of ageing populations is increasingly determined by age-related changes to the mechanical properties of numerous biological tissues. Degradation and mechanical failure of these tissues has a profound effect on human morbidity and mortality. Soft tissues have complex and intricate structures and, similar to engineering materials, their mechanical properties are controlled by their microstructure. Thus age-relate changes in mechanical behavior are determined by changes in the properties and relative quantities of microstructural tissue components. This review focuses on the cardiovascular system; it discusses the techniques used both in vivo and ex vivo to determine the age-related changes in the mechanical properties of arteries. © 2011 Elsevier Ltd.

Original language	English
Pages (from-to)	96-105
Number of pages	9
Journal	Materials Today
Volume	14
Issue number	3
DOIs	https://doi.org/10.1016/S1369-7021(11)70059-1
Publication status	Published - Mar 2011

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abstract = "The quality of life of ageing populations is increasingly determined by age-related changes to the mechanical properties of numerous biological tissues. Degradation and mechanical failure of these tissues has a profound effect on human morbidity and mortality. Soft tissues have complex and intricate structures and, similar to engineering materials, their mechanical properties are controlled by their microstructure. Thus age-relate changes in mechanical behavior are determined by changes in the properties and relative quantities of microstructural tissue components. This review focuses on the cardiovascular system; it discusses the techniques used both in vivo and ex vivo to determine the age-related changes in the mechanical properties of arteries. {\textcopyright} 2011 Elsevier Ltd.",

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N2 - The quality of life of ageing populations is increasingly determined by age-related changes to the mechanical properties of numerous biological tissues. Degradation and mechanical failure of these tissues has a profound effect on human morbidity and mortality. Soft tissues have complex and intricate structures and, similar to engineering materials, their mechanical properties are controlled by their microstructure. Thus age-relate changes in mechanical behavior are determined by changes in the properties and relative quantities of microstructural tissue components. This review focuses on the cardiovascular system; it discusses the techniques used both in vivo and ex vivo to determine the age-related changes in the mechanical properties of arteries. © 2011 Elsevier Ltd.

AB - The quality of life of ageing populations is increasingly determined by age-related changes to the mechanical properties of numerous biological tissues. Degradation and mechanical failure of these tissues has a profound effect on human morbidity and mortality. Soft tissues have complex and intricate structures and, similar to engineering materials, their mechanical properties are controlled by their microstructure. Thus age-relate changes in mechanical behavior are determined by changes in the properties and relative quantities of microstructural tissue components. This review focuses on the cardiovascular system; it discusses the techniques used both in vivo and ex vivo to determine the age-related changes in the mechanical properties of arteries. © 2011 Elsevier Ltd.

U2 - 10.1016/S1369-7021(11)70059-1

DO - 10.1016/S1369-7021(11)70059-1

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VL - 14

SP - 96

EP - 105

JO - Materials Today

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Characterizing the elastic properties of tissues

Abstract

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