Abstract
The mechanism of amine oxidation by flavoprotein enzymes is critically analysed through analysis of available experimental data. The review assesses available evidence for radical and polar mechanisms, drawing on data from model reactions, kinetic and spectroscopic approaches, structural and mutagenesis studies. The review focuses on studies of mammalian monoamine oxidases and the bacterial enzymes trimethylamine dehydrogenase, monomeric sarcosine oxidase and dimethylglycine oxidase.
| Original language | English |
|---|---|
| Pages (from-to) | 722-730 |
| Number of pages | 8 |
| Journal | Natural Product Reports |
| Volume | 21 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2004 |