Chemokine redundancy versus specificity in the context of CXCR3 and its ligands

Amanda Jl Ridley, Douglas Dyer

Research output: Contribution to journalEditorialpeer-review

Abstract

In a recent article published in Immunology & Cell Biology, Dalit et al. describe how correcting mutations in the C57BL/6 mouse strain can restore production of the chemokine CXCL11, although surprisingly, this expression of CXCL11 had little effect on B and T cells and the innate immune response to infection with lymphocytic choriomeningitis virus or influenza virus.

Original languageEnglish
Pages (from-to)387-389
Number of pages3
JournalImmunology and cell biology
Volume100
Issue number6
Early online date25 Apr 2022
DOIs
Publication statusPublished - 1 Jul 2022

Keywords

  • Animals
  • Arenaviridae Infections/immunology
  • B-Lymphocytes/immunology
  • Chemokine CXCL11/genetics
  • Chemokines
  • Immunity, Innate
  • Ligands
  • Lymphocytic choriomeningitis virus
  • Mice
  • Mice, Inbred C57BL
  • Receptors, CXCR3
  • T-Lymphocytes/immunology

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