Circulating Tumor Cells Detected in the Tumor-Draining Pulmonary Vein Are Associated with Disease Recurrence after Surgical Resection of NSCLC

Philip AJ Crosbie, Rajesh Shah, Piotr Krysiak, Cong Zhou, Karen Morris, Jonathan Tugwood, Richard Booton, Fiona Blackhall, Caroline Dive

Research output: Contribution to journalArticlepeer-review

Abstract

Tumor recurrence after surgical resection of NSCLC obstructs long-term disease-free survival in approximately 50% of cases. Our data suggest that combining circulating tumor cell enumeration (as single cells or clusters) in tumor-draining pulmonary vein and peripheral blood (assessed by CellSearch) at the time of NSCLC surgery better identifies those patients at higher risk for lung cancer recurrence than does peripheral circulating tumor cell number alone.

Original languageEnglish
Pages (from-to)1793-7
Number of pages5
JournalJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Volume11
Issue number10
Early online date25 Jul 2016
DOIs
Publication statusPublished - Oct 2016

Keywords

  • Journal Article

Fingerprint

Dive into the research topics of 'Circulating Tumor Cells Detected in the Tumor-Draining Pulmonary Vein Are Associated with Disease Recurrence after Surgical Resection of NSCLC'. Together they form a unique fingerprint.

Cite this