Citrobacter freundii and fatal neutropenic enterocolitis following adjuvant chemotherapy for breast cancer

M J Clemons, J W Valle, M Harris, S Ellenbogen, A Howell

Research output: Contribution to journalArticlepeer-review

Abstract

Neutropenic enterocolitis is increasingly being recognized as a life-threatening complication of chemotherapy, mainly for haematological and lymphoproliferative malignancies. It is under-recognized clinically, with the diagnosis often being made on post-mortem examination. Although active medical management is generally preferred, surgical intervention may be indicated. We report a case of fatal neutropenic enterocolitis, secondary to Citrobacter freundii, following adjuvant chemotherapy for breast cancer. We also review the literature, examining the aetiology, diagnosis and management of this often fatal entity.

Original languageEnglish
Pages (from-to)172-5
Number of pages4
JournalClinical oncology (Royal College of Radiologists (Great Britain))
Volume9
Issue number3
Publication statusPublished - 1997

Keywords

  • Antineoplastic Combined Chemotherapy Protocols
  • Bacteremia
  • Breast Neoplasms
  • Chemotherapy, Adjuvant
  • Citrobacter freundii
  • Enterobacteriaceae Infections
  • Enterocolitis
  • Fatal Outcome
  • Female
  • Humans
  • Middle Aged
  • Neutropenia
  • Case Reports
  • Journal Article

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