Clearing the undergrowth: detection and quantification of low level impurities using 19F NMR

Pinelopi Moutzouri; Peter Kiraly; Andrew R. Phillips; Steven Coombes; Mathias Nilsson; Gareth Morris

doi:10.1039/C6CC08836H

Clearing the undergrowth: detection and quantification of low level impurities using 19F NMR

Pinelopi Moutzouri, Peter Kiraly, Andrew R. Phillips, Steven Coombes, Mathias Nilsson, Gareth Morris

AstraZeneca

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Abstract

A new method for the analysis of low level impurities in sparsely fluorinated species allows measurement of clean high dynamic range 19F spectra, fully decoupled and free of interfering signals from 13C isotopomers.

Original language	English
Pages (from-to)	123-125
Journal	Chemical Communications
Volume	53
Early online date	23 Nov 2016
DOIs	https://doi.org/10.1039/C6CC08836H
Publication status	Published - 1 Jan 2017

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10.1039/C6CC08836HLicence: CC BY

CC-COM-11-2016-008836Final published version, 1.42 MBLicence: CC BY

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title = "Clearing the undergrowth: detection and quantification of low level impurities using 19F NMR",

abstract = "A new method for the analysis of low level impurities in sparsely fluorinated species allows measurement of clean high dynamic range 19F spectra, fully decoupled and free of interfering signals from 13C isotopomers.",

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AU - Nilsson, Mathias

AU - Morris, Gareth

PY - 2017/1/1

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JO - Chemical Communications

JF - Chemical Communications

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Clearing the undergrowth: detection and quantification of low level impurities using 19F NMR

Abstract

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