Clinical applications of corneal confocal microscopy.

Mitra Tavakoli, Parwez Hossain, Rayaz A Malik

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Corneal confocal microscopy is a novel clinical technique for the study of corneal cellular structure. It provides images which are comparable to in-vitro histochemical techniques delineating corneal epithelium, Bowman's layer, stroma, Descemet's membrane and the corneal endothelium. Because, corneal confocal microscopy is a non invasive technique for in vivo imaging of the living cornea it has huge clinical potential to investigate numerous corneal diseases. Thus far it has been used in the detection and management of pathologic and infectious conditions, corneal dystrophies and ecstasies, monitoring contact lens induced corneal changes and for pre and post surgical evaluation (PRK, LASIK and LASEK, flap evaluations and Radial Keratotomy), and penetrating keratoplasty. Most recently it has been used as a surrogate for peripheral nerve damage in a variety of peripheral neuropathies and may have potential in acting as a surrogate marker for endothelial abnormalities.
Original languageEnglish
Title of host publicationClinical ophthalmology (Auckland, N.Z.)
PublisherDove Medical Press Ltd
Number of pages11
ISBN (Print)1177-5467 (Print)\n1177-5467 (Linking)
Publication statusPublished - Jun 2008

Publication series

NameClinical ophthalmology (Auckland, N.Z.)


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