Clinical characteristics and survival in cardiogenic shock admissions to a UK heart transplant unit

Parminder S Chaggar, Ewan J Mckay, Philip Foden, Simon G Williams, Jim Barnard, Nizar Yonan, Rajamiyer Venkateswaran, Steven M Shaw

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: We describe the characteristics and outcomes of cardiogenic shock (CS) admissions to a UK transplant unit, which is previously unreported. Patients & methods: Fifty-nine unselected, consecutive patients over a 38-month period in CS (INTERMACS ≤2) and potentially eligible for transplant were retrospectively reviewed. Results: Patients were predominantly male (76.3%), young (mean age 42.2 years) and with severe end-organ dysfunction (acute liver/kidney injury 83%, mean lactate 3.5 mmol/l). 57.6% required mechanical support and 28.8% cardiac transplant. 30 days, discharge and 1-year survival were 78, 68 and 63%, respectively. Predictors of death included no transplant, increasing age and increasing creatinine. Conclusion: Patients with CS and potential for transplant require significant resource input but demonstrate favorable outcomes in our experience.
Original languageEnglish
Pages (from-to)397-406
Number of pages9
JournalFuture Cardiology
Volume14
Issue number5
Early online date20 Sept 2018
DOIs
Publication statusPublished - Sept 2018

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