TY - JOUR
T1 - Clinical trials in recurrent ovarian cancer
AU - Friedlander, Michael
AU - Trimble, Edward
AU - Tinker, Anna
AU - Alberts, David
AU - Avall-Lundqvist, Elisabeth
AU - Brady, Mark
AU - Harter, Philipp
AU - Pignata, Sandro
AU - Pujade-Lauraine, Eric
AU - Sehouli, Jalid
AU - Vergote, Ignace
AU - Beale, Philip
AU - Bekkers, Rudd
AU - Calvert, Paula
AU - Copeland, Lawrence
AU - Glasspool, Ros
AU - Gonzalez-Martin, Antonio
AU - Katsaros, Dionysis
AU - Kim, Jae Won
AU - Miller, Brigitte
AU - Provencher, Diane
AU - Rubinstein, Lawrence
AU - Atri, Mostafa
AU - Zeimet, Alain
AU - Bacon, Monica
AU - Kitchener, Henry
AU - Stuart, Gavin C E
PY - 2011/5
Y1 - 2011/5
N2 - The 4th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup was held in Vancouver, Canada, in June 2010. Representatives of 23 cooperative research groups studying gynecologic cancers gathered to establish international consensus on issues critical to the conduct of large randomized trials. Group C, 1 of the 3 discussion groups, examined recurrent ovarian cancer, and we report the consensus reached regarding 4 questions. These included the following: (1) What is the role of cytoreductive surgery for recurrent ovarian cancer? (2) How do we define distinct patient populations in need of specific therapeutic approaches? (3) Should end points for trials with recurrent disease vary from those of first-line trials? (4) Is CA-125 progression alone sufficient for entry/eligibility into clinical trials? Copyright © 2011 by IGCS and ESGO.
AB - The 4th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup was held in Vancouver, Canada, in June 2010. Representatives of 23 cooperative research groups studying gynecologic cancers gathered to establish international consensus on issues critical to the conduct of large randomized trials. Group C, 1 of the 3 discussion groups, examined recurrent ovarian cancer, and we report the consensus reached regarding 4 questions. These included the following: (1) What is the role of cytoreductive surgery for recurrent ovarian cancer? (2) How do we define distinct patient populations in need of specific therapeutic approaches? (3) Should end points for trials with recurrent disease vary from those of first-line trials? (4) Is CA-125 progression alone sufficient for entry/eligibility into clinical trials? Copyright © 2011 by IGCS and ESGO.
KW - Clinical trials
KW - Ovarian cancer
KW - Recurrent
U2 - 10.1097/IGC.0b013e31821bb8aa
DO - 10.1097/IGC.0b013e31821bb8aa
M3 - Article
SN - 1525-1438
VL - 21
SP - 771
EP - 775
JO - International Journal of Gynecological Cancer
JF - International Journal of Gynecological Cancer
IS - 4
ER -