Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene

J. D. Vargas; E. Culetto; C. P. Ponting; I. Miguel-Aliaga; K. E. Davies; D. B. Sattelle

doi:10.1016/S0925-4773(02)00182-X

Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene

J. D. Vargas
, E. Culetto
, C. P. Ponting
, I. Miguel-Aliaga
, K. E. Davies
, D. B. Sattelle

Research output: Contribution to journal › Article › peer-review

Abstract

We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has homologues in invertebrates, fungi and a cyanobacterium. The C. elegans Ky homologue gene has been named ltd-1 for LIM and transglutaminase domains gene. The LTD-1::GFP construct is expressed in developing hypodermal cells from the twofold stage embryo through adulthood. These data define the ltd-1 gene as a novel marker for C. elegans epithelial cell development. © 2002 Elsevier Science Ireland Ltd. All rights reserved.

Original language	English
Pages (from-to)	289-292
Number of pages	3
Journal	Mechanisms of Development
Volume	117
Issue number	1-2
DOIs	https://doi.org/10.1016/S0925-4773(02)00182-X
Publication status	Published - Sept 2002

Keywords

Caenorhabditis elegans
Development
Epithelial cells
Green fluorescent protein
Human genetic diseases
Hypodermal cells
ky gene
Kyphoscoliosis
LIM domain
Pharynx
Seam cells
Socket cells
Transglutaminase domain

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10.1016/S0925-4773(02)00182-X

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title = "Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene",

abstract = "We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has homologues in invertebrates, fungi and a cyanobacterium. The C. elegans Ky homologue gene has been named ltd-1 for LIM and transglutaminase domains gene. The LTD-1::GFP construct is expressed in developing hypodermal cells from the twofold stage embryo through adulthood. These data define the ltd-1 gene as a novel marker for C. elegans epithelial cell development. {\textcopyright} 2002 Elsevier Science Ireland Ltd. All rights reserved.",

keywords = "Caenorhabditis elegans, Development, Epithelial cells, Green fluorescent protein, Human genetic diseases, Hypodermal cells, ky gene, Kyphoscoliosis, LIM domain, Pharynx, Seam cells, Socket cells, Transglutaminase domain",

author = "Vargas, \{J. D.\} and E. Culetto and Ponting, \{C. P.\} and I. Miguel-Aliaga and Davies, \{K. E.\} and Sattelle, \{D. B.\}",

year = "2002",

month = sep,

doi = "10.1016/S0925-4773(02)00182-X",

language = "English",

volume = "117",

pages = "289--292",

journal = "Mechanisms of Development",

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publisher = "John Wiley \& Sons Ltd",

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T1 - Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene

AU - Vargas, J. D.

AU - Culetto, E.

AU - Ponting, C. P.

AU - Miguel-Aliaga, I.

AU - Davies, K. E.

AU - Sattelle, D. B.

PY - 2002/9

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N2 - We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has homologues in invertebrates, fungi and a cyanobacterium. The C. elegans Ky homologue gene has been named ltd-1 for LIM and transglutaminase domains gene. The LTD-1::GFP construct is expressed in developing hypodermal cells from the twofold stage embryo through adulthood. These data define the ltd-1 gene as a novel marker for C. elegans epithelial cell development. © 2002 Elsevier Science Ireland Ltd. All rights reserved.

AB - We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has homologues in invertebrates, fungi and a cyanobacterium. The C. elegans Ky homologue gene has been named ltd-1 for LIM and transglutaminase domains gene. The LTD-1::GFP construct is expressed in developing hypodermal cells from the twofold stage embryo through adulthood. These data define the ltd-1 gene as a novel marker for C. elegans epithelial cell development. © 2002 Elsevier Science Ireland Ltd. All rights reserved.

KW - Caenorhabditis elegans

KW - Development

KW - Epithelial cells

KW - Green fluorescent protein

KW - Human genetic diseases

KW - Hypodermal cells

KW - ky gene

KW - Kyphoscoliosis

KW - LIM domain

KW - Pharynx

KW - Seam cells

KW - Socket cells

KW - Transglutaminase domain

U2 - 10.1016/S0925-4773(02)00182-X

DO - 10.1016/S0925-4773(02)00182-X

M3 - Article

C2 - 12204272

SN - 0925-4773

VL - 117

SP - 289

EP - 292

JO - Mechanisms of Development

JF - Mechanisms of Development

IS - 1-2

ER -

Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene

Abstract

Keywords

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