Clostridium difficile, atopy and wheeze during the first year of life

Ashley Woodcock, Mohammad Moradi, Frazer I. Smillie, Clare S. Murray, James P. Burnie, Adnan Custovic

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Differences have been suggested to occur in the composition of intestinal microflora from allergic and non-allergic children. In this study we used a semi-quantitative enzyme-linked immunosorbent assay (ELISA) for the measurement of Clostridium difficile-specific immunoglobulin G (IgG) (CDIgG). CDIgG was excellent in differentiating between adults with or without Cl. difficile colitis (absorbance levels, positive vs. negative controls: geometric mean (GM) 0.301, 95% CI: 0.289-0.314 vs. GM 0.167, 95% CI: 0.155-0.181; mean difference 1.8-fold, 95% CI: 1.65-1.95; p
    Original languageEnglish
    Pages (from-to)357-360
    Number of pages3
    JournalPediatric Allergy and Immunology
    Volume13
    Issue number5
    DOIs
    Publication statusPublished - Oct 2002

    Keywords

    • Asthma
    • Atopy
    • Clostridium difficile
    • Intestinal microflora

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