Cofactor regeneration

Fraser A. Armstrong (Inventor), Clare Megarity (Inventor), Giorgio Morello (Inventor)

Research output: Patent

Abstract

An electrochemical system comprising an electrode (D) having a porous layer and plural enzymes and a cofactor (ATP) located within the pores of the porous layer, a first of said plural enzymes (E1) being operable to recycle nicotinamide cofactors (N) in response to an electrical stimulus, a second of said plural enzymes (E2) being operable to convert a second species (K2) to a first species (K1) in the presence of a nicotinamide cofactor (N) and a third of said plural enzymes (E3) being operable to convert a reactant (R) to a third species (P), wherein one or both of the second (E2) and third (E3) of said plural enzymes are operable to convert the respective second species and reactant in the presence of the cofactor (ATP).
Original languageEnglish
Patent numberPCT/GB2023/051749
IPCG01N 33/573 2006.1,C12Q 1/00 2006.1,C12Q 1/26 2006.1,C12Q 1/48 2006.1,C12Q 1/32 2006.1
Priority date4/07/22
Filing date4/07/23
Publication statusPublished - 11 Jan 2024

Keywords

  • ATP
  • NADP(H) electrochemical regeneration

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