Cold atmospheric pressure plasma jet interactions with plasmid DNA

D. O'Connell, L. J. Cox, W. B. Hyland, S. J. McMahon, S. Reuter, W. G. Graham, T. Gans, F. J. Currell

Research output: Contribution to journalArticlepeer-review


The effect of a cold (<40 °C) radio frequency-driven atmospheric pressure plasma jet on plasmid DNA has been investigated. Gel electrophoresis was used to analyze the DNA forms post-treatment. The experimental data are fitted to a rate equation model that allows for quantitative determination of the rates of single and double strand break formation. The formation of double strand breaks correlates well with the atomic oxygen density. Taken with other measurements, this indicates that neutral components in the jet are effective in inducing double strand breaks.
Original languageEnglish
Number of pages4
JournalApplied Physics Letters
Issue number4
Publication statusPublished - 24 Jan 2011

Research Beacons, Institutes and Platforms

  • Dalton Nuclear Institute


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