TY - JOUR
T1 - Colorectal carcinoma to pituitary tumour
T2 - tumour to tumour metastasis
AU - Donofrio, Carmine Antonio
AU - Pizzimenti, Cristina
AU - Djoukhadar, Ibrahim
AU - Kearney, Tara
AU - Gnanalingham, Kanna
AU - Roncaroli, Federico
PY - 2020/9/21
Y1 - 2020/9/21
N2 - We document a patient with colon adenocarcinoma who presented with rapidly worsening visual impairment. Staging computer tomography and subsequent magnetic resonance scans documented a sellar, suprasellar lesion compressing the optic chiasm. The patient underwent trans-sphenoidal surgery to relieve optic chiasm compression and obtain tissue for diagnosis. Histological examination revealed a metastatic mucinous adenocarcinoma in a gonadotroph pituitary neuroendocrine tumour (PitNET, formerly pituitary adenoma). The patient underwent adjuvant radiotherapy to the sella and chemotherapy but he died nine months after pituitary surgery. This report highlights the diagnostic and management challenges of metastases to PitNET.
AB - We document a patient with colon adenocarcinoma who presented with rapidly worsening visual impairment. Staging computer tomography and subsequent magnetic resonance scans documented a sellar, suprasellar lesion compressing the optic chiasm. The patient underwent trans-sphenoidal surgery to relieve optic chiasm compression and obtain tissue for diagnosis. Histological examination revealed a metastatic mucinous adenocarcinoma in a gonadotroph pituitary neuroendocrine tumour (PitNET, formerly pituitary adenoma). The patient underwent adjuvant radiotherapy to the sella and chemotherapy but he died nine months after pituitary surgery. This report highlights the diagnostic and management challenges of metastases to PitNET.
U2 - 10.1080/02688697.2020.1823937
DO - 10.1080/02688697.2020.1823937
M3 - Article
C2 - 32955367
SN - 0268-8697
SP - 1
EP - 4
JO - British journal of neurosurgery
JF - British journal of neurosurgery
ER -
