Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus

D. C. Whiteman; S. Sadeghi; N. Pandeya; B. M. Smithers; D. C. Gotley; C. J. Bain; P. M. Webb; A. C. Green

doi:10.1136/gut.2007.131375

Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus

D. C. Whiteman, S. Sadeghi, N. Pandeya, B. M. Smithers, D. C. Gotley, C. J. Bain, P. M. Webb, A. C. Green

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To measure the relative risks of adenocarcinomas of the oesophagus and gastro-oesophageal junction associated with measures of obesity, and their interactions with age, sex, gastro-oesophageal reflux symptoms and smoking. Design and setting: Population-based case-control study in Australia. Patients: Patients with adenocarcinomas of the oesophagus (n = 367) or gastro-oesophageal junction (n = 426) were compared with control participants (n = 1580) sampled from a population register. Main outcome measure: Relative risk of adenocarcinoma of the oesophagus or gastro-oesophageal junction. Results: Risks of oesophageal adenocarcinoma increased monotonically with body mass index (BMI) (ptrend

Original language	English
Pages (from-to)	173-180
Number of pages	7
Journal	Gut
Volume	57
Issue number	2
DOIs	https://doi.org/10.1136/gut.2007.131375
Publication status	Published - Feb 2008

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10.1136/gut.2007.131375

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abstract = "Objective: To measure the relative risks of adenocarcinomas of the oesophagus and gastro-oesophageal junction associated with measures of obesity, and their interactions with age, sex, gastro-oesophageal reflux symptoms and smoking. Design and setting: Population-based case-control study in Australia. Patients: Patients with adenocarcinomas of the oesophagus (n = 367) or gastro-oesophageal junction (n = 426) were compared with control participants (n = 1580) sampled from a population register. Main outcome measure: Relative risk of adenocarcinoma of the oesophagus or gastro-oesophageal junction. Results: Risks of oesophageal adenocarcinoma increased monotonically with body mass index (BMI) (ptrend",

author = "Whiteman, {D. C.} and S. Sadeghi and N. Pandeya and Smithers, {B. M.} and Gotley, {D. C.} and Bain, {C. J.} and Webb, {P. M.} and Green, {A. C.}",

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T1 - Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus

AU - Whiteman, D. C.

AU - Sadeghi, S.

AU - Pandeya, N.

AU - Smithers, B. M.

AU - Gotley, D. C.

AU - Bain, C. J.

AU - Webb, P. M.

AU - Green, A. C.

PY - 2008/2

Y1 - 2008/2

N2 - Objective: To measure the relative risks of adenocarcinomas of the oesophagus and gastro-oesophageal junction associated with measures of obesity, and their interactions with age, sex, gastro-oesophageal reflux symptoms and smoking. Design and setting: Population-based case-control study in Australia. Patients: Patients with adenocarcinomas of the oesophagus (n = 367) or gastro-oesophageal junction (n = 426) were compared with control participants (n = 1580) sampled from a population register. Main outcome measure: Relative risk of adenocarcinoma of the oesophagus or gastro-oesophageal junction. Results: Risks of oesophageal adenocarcinoma increased monotonically with body mass index (BMI) (ptrend

AB - Objective: To measure the relative risks of adenocarcinomas of the oesophagus and gastro-oesophageal junction associated with measures of obesity, and their interactions with age, sex, gastro-oesophageal reflux symptoms and smoking. Design and setting: Population-based case-control study in Australia. Patients: Patients with adenocarcinomas of the oesophagus (n = 367) or gastro-oesophageal junction (n = 426) were compared with control participants (n = 1580) sampled from a population register. Main outcome measure: Relative risk of adenocarcinoma of the oesophagus or gastro-oesophageal junction. Results: Risks of oesophageal adenocarcinoma increased monotonically with body mass index (BMI) (ptrend

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DO - 10.1136/gut.2007.131375

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SN - 0017-5749

VL - 57

SP - 173

EP - 180

JO - Gut

JF - Gut

IS - 2

ER -

Combined effects of obesity, acid reflux and smoking on the risk of adenocarcinomas of the oesophagus

Abstract

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