Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone

Paul A Brough, Xavier Barril, Jenifer Borgognoni, Patrick Chene, Nicholas G M Davies, Ben Davis, Martin J Drysdale, Brian Dymock, Suzanne A Eccles, Carlos Garcia-Echeverria, Christophe Fromont, Angela Hayes, Roderick E Hubbard, Allan M Jordan, Michael Rugaard Jensen, Andrew Massey, Angela Merrett, Antony Padfield, Rachel Parsons, Thomas RadimerskiFlorence I Raynaud, Alan Robertson, Stephen D Roughley, Joseph Schoepfer, Heather Simmonite, Swee Y Sharp, Allan Surgenor, Melanie Valenti, Steven Walls, Paul Webb, Mike Wood, Paul Workman, Lisa Wright

Research output: Contribution to journal › Article › peer-review

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Biochemistry, Genetics and Molecular Biology