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Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone

  • Paul A Brough
  • , Xavier Barril
  • , Jenifer Borgognoni
  • , Patrick Chene
  • , Nicholas G M Davies
  • , Ben Davis
  • , Martin J Drysdale
  • , Brian Dymock
  • , Suzanne A Eccles
  • , Carlos Garcia-Echeverria
  • , Christophe Fromont
  • , Angela Hayes
  • , Roderick E Hubbard
  • , Allan M Jordan
  • , Michael Rugaard Jensen
  • , Andrew Massey
  • , Angela Merrett
  • , Antony Padfield
  • , Rachel Parsons
  • , Thomas Radimerski
    • Florence I Raynaud, Alan Robertson, Stephen D Roughley, Joseph Schoepfer, Heather Simmonite, Swee Y Sharp, Allan Surgenor, Melanie Valenti, Steven Walls, Paul Webb, Mike Wood, Paul Workman, Lisa Wright

Research output: Contribution to journal › Article › peer-review

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Biochemistry, Genetics and Molecular Biology