Commercial mouthwashes are more effective than azole antifungals against Candida albicans biofilms in vitro

Gordon Ramage, Anto Jose, Brent Coco, Ranjith Rajendran, Rautemaa-Richardson Richardson, Colin Murray, David F. Lappin, Jeremy Bagg

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective The aim of this study was to evaluate and compare the activity of prescription and over-the-counter antimicrobial compounds against planktonic and biofilm forms of Candida albicans isolated from cases of oral candidiasis in vitro. Study design The efficacy of azoles, polyenes, an echinocandin, and 4 over-the-counter mouthwashes were tested against C. albicansderived planktonic and biofilm cells. Results Planktonic cells were shown to be highly sensitive to all of the antifungal agents tested. Sessile cells were highly resistant to azoles (
    Original languageEnglish
    Pages (from-to)456-460
    Number of pages4
    JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics
    Volume111
    Issue number4
    DOIs
    Publication statusPublished - Apr 2011

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