TY - JOUR
T1 - Commercial mouthwashes are more effective than azole antifungals against Candida albicans biofilms in vitro
AU - Ramage, Gordon
AU - Jose, Anto
AU - Coco, Brent
AU - Rajendran, Ranjith
AU - Richardson, Rautemaa-Richardson
AU - Murray, Colin
AU - Lappin, David F.
AU - Bagg, Jeremy
N1 - CZG/1/152, Chief Scientist Office, United Kingdom
PY - 2011/4
Y1 - 2011/4
N2 - Objective The aim of this study was to evaluate and compare the activity of prescription and over-the-counter antimicrobial compounds against planktonic and biofilm forms of Candida albicans isolated from cases of oral candidiasis in vitro. Study design The efficacy of azoles, polyenes, an echinocandin, and 4 over-the-counter mouthwashes were tested against C. albicansderived planktonic and biofilm cells. Results Planktonic cells were shown to be highly sensitive to all of the antifungal agents tested. Sessile cells were highly resistant to azoles (
AB - Objective The aim of this study was to evaluate and compare the activity of prescription and over-the-counter antimicrobial compounds against planktonic and biofilm forms of Candida albicans isolated from cases of oral candidiasis in vitro. Study design The efficacy of azoles, polyenes, an echinocandin, and 4 over-the-counter mouthwashes were tested against C. albicansderived planktonic and biofilm cells. Results Planktonic cells were shown to be highly sensitive to all of the antifungal agents tested. Sessile cells were highly resistant to azoles (
U2 - 10.1016/j.tripleo.2010.10.043
DO - 10.1016/j.tripleo.2010.10.043
M3 - Article
C2 - 21310633
SN - 1528-395X
VL - 111
SP - 456
EP - 460
JO - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics
JF - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics
IS - 4
ER -