Common germline polymorphisms associated with breast cancer-specific survival.

Ailith Pirie, Qi Guo, Peter Kraft, Sander Canisius, Diana M Eccles, Nazneen Rahman, Heli Nevanlinna, Constance Chen, Sofia Khan, Jonathan Tyrer, Manjeet K Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Michael Lush, Alison M Dunning, Mitul Shah, Kamila Czene, Hatef Darabi, Mikael ErikssonDieter Lambrechts, Caroline Weltens, Karin Leunen, Chantal van Ongeval, Børge G Nordestgaard, Sune F Nielsen, Henrik Flyger, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Carl Blomqvist, Kristiina Aittomäki, Rainer Fagerholm, Taru A Muranen, Janet E Olsen, Emily Hallberg, Celine Vachon, Julia A Knight, Gord Glendon, Anna Marie Mulligan, Annegien Broeks, Sten Cornelissen, Christopher A Haiman, Brian E Henderson, Frederick Schumacher, Loic Le Marchand, John L Hopper, Helen Tsimiklis, Carmel Apicella, Melissa C Southey, Simon S Cross, Malcolm Wr Reed, Graham G Giles, Roger L Milne, Catriona McLean, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Maartje J Hooning, Antoinette Hollestelle, John Wm Martens, Ans Mw van den Ouweland, Federick Marme, Andreas Schneeweiss, Rongxi Yang, Barbara Burwinkel, Jonine Figueroa, Stephen J Chanock, Jolanta Lissowska, Elinor J Sawyer, Ian Tomlinson, Michael J Kerin, Nicola Miller, Hermann Brenner, Katja Butterbach, Bernd Holleczek, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Jingmei Li, Judith S Brand, Keith Humphreys, Peter Devilee, Robert Aem Tollenaar, Caroline Seynaeve, Paolo Radice, Paolo Peterlongo, Siranoush Manoukian, Filomena Ficarazzi, Matthias W Beckmann, Alexander Hein, Arif B Ekici, Rosemary Balleine, Kelly-Anne Phillips, Javier Benitez, M Pilar Zamora, Jose Ignacio Arias Perez, Primitiva Menéndez, Anna Jakubowska, Jan Lubinski, Jacek Gronwald, Katarzyna Durda, Ute Hamann, Maria Kabisch, Hans Ulrich Ulmer, Thomas Rüdiger, Sara Margolin, Vessela Kristensen, Siljie Nord, D Gareth Evans, Jean Abraham, Helena Earl, Christopher J Poole, Louise Hiller, Janet A Dunn, Sarah Bowden, Rose Yang, Daniele Campa, W Ryan Diver, Susan M Gapstur, Mia M Gaudet, Susan Hankinson, Robert N Hoover, Anika Hüsing, Rudolf Kaaks, Mitchell J Machiela, Walter Willett, Myrto Barrdahl, Federico Canzian, Suet-Feung Chin, Carlos Caldas, David J Hunter, Sara Lindstrom, Montserrat Garcia-Closas, Fergus J Couch, Georgia Chenevix-Trench, Arto Mannermaa, Irene L Andrulis, Per Hall, Jenny Chang-Claude, Douglas F Easton, Stig E Bojesen, Angela Cox, Peter A Fasching, Paul Dp Pharoah, Marjanka K Schmidt

    Research output: Contribution to journalArticlepeer-review

    Abstract

    INTRODUCTION: Previous studies have identified common germline variants nominally associated with breast cancer survival. These associations have not been widely replicated in further studies. The purpose of this study was to evaluate the association of previously reported SNPs with breast cancer-specific survival using data from a pooled analysis of eight breast cancer survival genome-wide association studies (GWAS) from the Breast Cancer Association Consortium. METHODS: A literature review was conducted of all previously published associations between common germline variants and three survival outcomes: breast cancer-specific survival, overall survival and disease-free survival. All associations that reached the nominal significance level of P value
    Original languageEnglish
    JournalBreast cancer research : BCR
    Volume17
    DOIs
    Publication statusPublished - 2015

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