Comparative personal exposures to organic dusts and endotoxin

J. C G Simpson, R. McL Niven, C. A C Pickering, L. A. Oldham, A. M. Fletcher, H. C. Francis

    Research output: Contribution to journalArticlepeer-review


    The aims of the study were to provide valid comparative data for personal exposures to dust and endotoxins for different occupations and to calculate comparative data for the contamination of organic dusts with endotoxin.Nine different occupational settings were studied, drawn from the textile, agricultural and animal handling industries. Samples were collected by personal sampling techniques, using the Institute of Occupational Medicine (IOM) sampling head, glass fibre filters and rechargeable sampling pumps. The dust exposures were calculated by gravimetric analysis and using the calculated volume of air sampled were expressed as mg/m3. Endotoxin exposures were measured using a simple water extraction from the collected dusts, followed by a quantitative turbidimetric assay. Results were expressed as ng/m3, using the calculated volume of air sampled. In addition, the levels of the contamination of dusts with endotoxin for individual industries were expressed as ng/mg of collected dust.Two hundred and fifty nine samples, collected from 9 different industries and across 36 different sites were analysed. This represented a sampling rate of 25% for the total work force. The average sampling time was 4.62 h. For all the dusts collected, a significant correlation between the collected dust and endotoxin was seen (r = 0.7 and p
    Original languageEnglish
    Pages (from-to)107-115
    Number of pages8
    JournalAnnals of Occupational Hygiene
    Issue number2
    Publication statusPublished - Feb 1999


    • Dust
    • Endotoxin
    • Organic dust


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