Comparison of cerebral blood volume maps generated from T2* and T1 weighted MRI data in intra-axial cerebral tumours

H. A. Haroon, T. F. Patankar, X. P. Zhu, K. L. Li, N. A. Thacker, M. J. Scott, Alan Jackson

    Research output: Contribution to journalArticlepeer-review

    Abstract

    We compared parametric maps, measured values and value distributions of cerebral blood volume (CBV) derived from (1) first pass T1 weighted dynamic contrast-enhanced (DCE) data (T1-CBV) using the recently described leakage profile model and (2) conventional T2* weighted DCE data (T2 *-CBV) using a conventional curve fitting technique, in nine patients with intraaxial tumours. Regions of interest were defined around enhancing tumour tissue on matched slices. Median tumour values and conspicuity indexes of CBV from the two techniques were compared, demonstrating good correlation (r=0.667,p
    Original languageEnglish
    Pages (from-to)161-168
    Number of pages7
    JournalBritish Journal of Radiology
    Volume80
    Issue number951
    DOIs
    Publication statusPublished - Mar 2007

    Keywords

    • Adult
    • Aged
    • Blood Volume
    • Brain Neoplasms/*blood supply
    • *Cerebrovascular Circulation
    • Female
    • Glioma/*blood supply
    • Humans
    • Image Processing, Computer-Assisted/methods
    • Magnetic Resonance Imaging/*methods
    • Male
    • Middle Aged
    • Neovascularization, Pathologic/*physiopathology

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