TY - JOUR
T1 - Comparison of steady-state and transient blood flow simulations of intracranial aneurysms.
AU - Geers, AJ
AU - Larrabide, I
AU - Morales, HG
AU - Frangi, AF
PY - 2010
Y1 - 2010
N2 - Hemodynamics play an important role in the pathogenesis of intracranial aneurysms and patient-specific computational hemodynamic simulations could provide valuable information to clinicians. Transient simulations that capture the pulsatility of blood flow are commonly used for research purposes. However, steady-state simulations might provide enough information at a lower computational cost, which could help facilitate the introduction of hemodynamic simulations into clinical practice. In this study, we compared steady-state simulations to transient simulations for two aneurysms. The effect of a change in flow rate waveform was investigated and virtual treatment techniques were employed to compare post-treatment flow reduction predictions. We found that the difference in the time-averaged wall shear stress on the aneurysm was less than 5% and the distribution of wall shear stress was qualitatively assessed to be very similar.
AB - Hemodynamics play an important role in the pathogenesis of intracranial aneurysms and patient-specific computational hemodynamic simulations could provide valuable information to clinicians. Transient simulations that capture the pulsatility of blood flow are commonly used for research purposes. However, steady-state simulations might provide enough information at a lower computational cost, which could help facilitate the introduction of hemodynamic simulations into clinical practice. In this study, we compared steady-state simulations to transient simulations for two aneurysms. The effect of a change in flow rate waveform was investigated and virtual treatment techniques were employed to compare post-treatment flow reduction predictions. We found that the difference in the time-averaged wall shear stress on the aneurysm was less than 5% and the distribution of wall shear stress was qualitatively assessed to be very similar.
UR - http://europepmc.org/abstract/med/21096183
U2 - 10.1109/iembs.2010.5626609
DO - 10.1109/iembs.2010.5626609
M3 - Conference article
C2 - 21096183
SN - 1557-170X
JO - IEEE Engineering in Medicine and Biology Society. Conference Proceedings
JF - IEEE Engineering in Medicine and Biology Society. Conference Proceedings
ER -