Comparison of two fluorescent whiteners, Calcofluor and Blankophor, for the detection of fungal elements in clinical specimens in the diagnostic laboratory

    Research output: Contribution to journalArticlepeer-review

    146 Downloads (Pure)

    Abstract

    Fluorescent whiteners, such as Blankophor and Calcofluor white, bind to chitin and cellulose, and fluoresce when exposed to UV light. Detection of fungal elements from skin and nail samples was faster and more accurate using Blankophor compared with potassium hydroxide preparations and Calcofluor (sensitivity and specificity 100% and 86% vs. 83-90% and 84-88%, or 80% and 84%, respectively). Visibility was improved, and the procedures were simple, inexpensive and rapid, all of which are important considerations in a busy diagnostic laboratory. © 2006 European Society of Clinical Microbiology and Infectious Diseases.
    Original languageEnglish
    Pages (from-to)181-184
    Number of pages3
    JournalClinical Microbiology and Infection
    Volume12
    Issue number2
    DOIs
    Publication statusPublished - Feb 2006

    Keywords

    • Blankophor
    • Calcofluor white
    • Dermatology
    • Diagnosis
    • Fluorescent whiteners
    • Fungal elements

    Fingerprint

    Dive into the research topics of 'Comparison of two fluorescent whiteners, Calcofluor and Blankophor, for the detection of fungal elements in clinical specimens in the diagnostic laboratory'. Together they form a unique fingerprint.

    Cite this