Composite Scaffolds for Large Bone Defects

Evangelos Daskalakis; Enes Aslan; Fengyuan Liu; Glen Cooper; Andrew Weightman; Bahattin Koc; Gordon Blunn; Paulo Jorge Da Silva Bartolo

doi:10.1007/978-3-030-29041-2_31

Composite Scaffolds for Large Bone Defects

Evangelos Daskalakis, Enes Aslan, Fengyuan Liu, Glen Cooper, Andrew Weightman, Bahattin Koc, Gordon Blunn, Paulo Jorge Da Silva Bartolo

Research output: Chapter in Book/Conference proceeding › Chapter › peer-review

Abstract

This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

Original language	English
Title of host publication	Progress in Digital and Physical Manufacturing
Subtitle of host publication	Procceedings of ProDPM'19
Editors	Henrique A Almeida, Joel C Vasco
Publisher	Springer Nature
Pages	250-257
Number of pages	8
ISBN (Electronic)	9783030290412
ISBN (Print)	9783030290405
DOIs	https://doi.org/10.1007/978-3-030-29041-2_31
Publication status	Published - 29 Sept 2019

Publication series

Name	Lecture Notes in Mechanical Engineering

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10.1007/978-3-030-29041-2_31

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Daskalakis, E., Aslan, E., Liu, F., Cooper, G., Weightman, A., Koc, B., Blunn, G., & Da Silva Bartolo, P. J. (2019). Composite Scaffolds for Large Bone Defects. In H. A. Almeida, & J. C. Vasco (Eds.), Progress in Digital and Physical Manufacturing: Procceedings of ProDPM'19 (pp. 250-257). (Lecture Notes in Mechanical Engineering). Springer Nature. https://doi.org/10.1007/978-3-030-29041-2_31

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title = "Composite Scaffolds for Large Bone Defects",

abstract = "This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization. ",

author = "Evangelos Daskalakis and Enes Aslan and Fengyuan Liu and Glen Cooper and Andrew Weightman and Bahattin Koc and Gordon Blunn and {Da Silva Bartolo}, {Paulo Jorge}",

year = "2019",

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day = "29",

doi = "10.1007/978-3-030-29041-2_31",

language = "English",

isbn = "9783030290405",

series = "Lecture Notes in Mechanical Engineering",

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pages = "250--257",

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}

Daskalakis, E, Aslan, E, Liu, F, Cooper, G , Weightman, A, Koc, B, Blunn, G & Da Silva Bartolo, PJ 2019, Composite Scaffolds for Large Bone Defects. in HA Almeida & JC Vasco (eds), Progress in Digital and Physical Manufacturing: Procceedings of ProDPM'19. Lecture Notes in Mechanical Engineering, Springer Nature, pp. 250-257. https://doi.org/10.1007/978-3-030-29041-2_31

Composite Scaffolds for Large Bone Defects. / Daskalakis, Evangelos; Aslan, Enes; Liu, Fengyuan et al.
Progress in Digital and Physical Manufacturing: Procceedings of ProDPM'19. ed. / Henrique A Almeida; Joel C Vasco. Springer Nature, 2019. p. 250-257 (Lecture Notes in Mechanical Engineering).

Research output: Chapter in Book/Conference proceeding › Chapter › peer-review

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T1 - Composite Scaffolds for Large Bone Defects

AU - Daskalakis, Evangelos

AU - Aslan, Enes

AU - Liu, Fengyuan

AU - Cooper, Glen

AU - Weightman, Andrew

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AU - Blunn, Gordon

AU - Da Silva Bartolo, Paulo Jorge

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N2 - This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

AB - This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

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DO - 10.1007/978-3-030-29041-2_31

M3 - Chapter

SN - 9783030290405

T3 - Lecture Notes in Mechanical Engineering

SP - 250

EP - 257

BT - Progress in Digital and Physical Manufacturing

A2 - Almeida, Henrique A

A2 - Vasco, Joel C

PB - Springer Nature

ER -

Composite Scaffolds for Large Bone Defects

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