Computational modelling of kinase signalling cascades.

David Gilbert, Monika Heiner, Rainer Breitling, Richard Orton

    Research output: Contribution to journalArticlepeer-review


    In this chapter, we describe general methods used to create dynamic computational models of kinase signalling cascades, and tools to support this activity. We focus on the ordinary differential equation models, and show how these fit into a general framework of qualitative and quantitative (stochastic and continuous) models. The modelling we describe is part of the activity of BioModel engineering which provides a systematic approach for designing, constructing, and analyzing computational models of biological systems.
    Original languageEnglish
    Pages (from-to)369-384
    Number of pages15
    JournalMethods in Molecular Biology
    Publication statusPublished - 2010


    Dive into the research topics of 'Computational modelling of kinase signalling cascades.'. Together they form a unique fingerprint.

    Cite this