Conserved RNA motifs of EMCV IRES as potential building blocks to design RNA nanostructures

Kwong Kit Chan, Vasudevan Ramesh

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The highly conserved secondary structural RNA motifs endowed by the IRES element of EMCV picornavirus provide an excellent platform to design RNA nanostructures for application in medicine. We have identified a 44mer RNA, hosting distinct 15mer and 11mer RNA stem loop motifs, as potential building blocks for the design of RNA nanostructures. This journal is © The Royal Society of Chemistry 2012.
    Original languageEnglish
    Pages (from-to)11573-11575
    Number of pages2
    JournalChemical Communications
    Volume48
    Issue number94
    DOIs
    Publication statusPublished - 7 Dec 2012

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