Contamination of stainless steel in an electrospray ionization source

J. Doff; D. Douce; G. Jones; E. V. Koroleva; P. Skeldon; G. E. Thompson

doi:10.1016/j.apsusc.2012.02.014

Contamination of stainless steel in an electrospray ionization source

J. Doff
, D. Douce
, G. Jones
, E. V. Koroleva
, P. Skeldon
, G. E. Thompson

Research output: Contribution to journal › Article › peer-review

Abstract

The contamination of the surface of 316L stainless steel in the electrospray ionization source of a mass spectrometer is investigated using an accelerated method of contamination from a mixture of human blood plasma, diluted in methanol, and a water/acetonitrile mobile phase. Solid contaminants containing organic and inorganic components are identified. The morphology and composition of the contamination are shown to depend upon the orientation and temperature of the stainless steel, with the morphology showing self-organizing features as the contamination builds. A model is proposed to explain the morphology, involving rapid evaporation of the droplets that impinge on the stainless steel surface. © 2012 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	5270-5282
Number of pages	12
Journal	Applied Surface Science
Volume	258
Issue number	13
DOIs	https://doi.org/10.1016/j.apsusc.2012.02.014
Publication status	Published - 15 Apr 2012

Keywords

Contamination
Electrospray
Mass spectrometer
Stainless steel

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10.1016/j.apsusc.2012.02.014

Light Alloys towards environmentally sustainable transport: 2nd generation solutions for Advanced Metallic Systems ( LATEST 2 )
Thompson, G. (PI), Bate, P. (CoI), Prangnell, P. (CoI), Preuss, M. (CoI), Quinta Da Fonseca, J. (CoI), Robson, J. (CoI), Skeldon, P. (CoI) & Zhou, X. (CoI)
1/02/10 → 31/07/15
Project: Research

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title = "Contamination of stainless steel in an electrospray ionization source",

abstract = "The contamination of the surface of 316L stainless steel in the electrospray ionization source of a mass spectrometer is investigated using an accelerated method of contamination from a mixture of human blood plasma, diluted in methanol, and a water/acetonitrile mobile phase. Solid contaminants containing organic and inorganic components are identified. The morphology and composition of the contamination are shown to depend upon the orientation and temperature of the stainless steel, with the morphology showing self-organizing features as the contamination builds. A model is proposed to explain the morphology, involving rapid evaporation of the droplets that impinge on the stainless steel surface. {\textcopyright} 2012 Elsevier B.V. All rights reserved.",

keywords = "Contamination, Electrospray, Mass spectrometer, Stainless steel",

author = "J. Doff and D. Douce and G. Jones and Koroleva, \{E. V.\} and P. Skeldon and Thompson, \{G. E.\}",

year = "2012",

month = apr,

day = "15",

doi = "10.1016/j.apsusc.2012.02.014",

language = "English",

volume = "258",

pages = "5270--5282",

journal = "Applied Surface Science",

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TY - JOUR

T1 - Contamination of stainless steel in an electrospray ionization source

AU - Doff, J.

AU - Douce, D.

AU - Jones, G.

AU - Koroleva, E. V.

AU - Skeldon, P.

AU - Thompson, G. E.

PY - 2012/4/15

Y1 - 2012/4/15

N2 - The contamination of the surface of 316L stainless steel in the electrospray ionization source of a mass spectrometer is investigated using an accelerated method of contamination from a mixture of human blood plasma, diluted in methanol, and a water/acetonitrile mobile phase. Solid contaminants containing organic and inorganic components are identified. The morphology and composition of the contamination are shown to depend upon the orientation and temperature of the stainless steel, with the morphology showing self-organizing features as the contamination builds. A model is proposed to explain the morphology, involving rapid evaporation of the droplets that impinge on the stainless steel surface. © 2012 Elsevier B.V. All rights reserved.

AB - The contamination of the surface of 316L stainless steel in the electrospray ionization source of a mass spectrometer is investigated using an accelerated method of contamination from a mixture of human blood plasma, diluted in methanol, and a water/acetonitrile mobile phase. Solid contaminants containing organic and inorganic components are identified. The morphology and composition of the contamination are shown to depend upon the orientation and temperature of the stainless steel, with the morphology showing self-organizing features as the contamination builds. A model is proposed to explain the morphology, involving rapid evaporation of the droplets that impinge on the stainless steel surface. © 2012 Elsevier B.V. All rights reserved.

KW - Contamination

KW - Electrospray

KW - Mass spectrometer

KW - Stainless steel

U2 - 10.1016/j.apsusc.2012.02.014

DO - 10.1016/j.apsusc.2012.02.014

M3 - Article

VL - 258

SP - 5270

EP - 5282

JO - Applied Surface Science

JF - Applied Surface Science

IS - 13

ER -

Contamination of stainless steel in an electrospray ionization source

Abstract

Keywords

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Light Alloys towards environmentally sustainable transport: 2nd generation solutions for Advanced Metallic Systems ( LATEST 2 )

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