"Contextual" synthetic lethality and/or loss of heterozygosity: Tumor hypoxia and modification of DNA repair

Biochemistry, Genetics and Molecular Biology

• Loss of Heterozygosity 100%
• Tumor Hypoxia 100%
• DNA Repair 100%
• Metabolic Pathway 50%
• Cell Genetics 50%
• Nucleotide Excision Repair 50%
• Oxygenation 50%
• Carcinogenesis 50%
• DNA Mismatch Repair 50%
• Base Excision Repair 50%