Convergence of Theory and Experiment on the Role of Preorganization, Quantum Tunneling, and Enzyme Motions into Flavoenzyme-Catalyzed Hydride Transfer

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• Finished

  Heavy enzymes: Probing fast dynamics in enzyme catalysis by mass modulation

  Hay, S. (PI) & Scrutton, N. (CoI)

  1/01/15 → 31/12/17

  Project: Research

  • Oxidoreductase 100%
  • Reductase 97%
  • Dynamics 75%
  • Flavoprotein 65%
  • Transfer Reaction 54%

• Linking experiment to theory: Quantum entanglement during enzyme catalysis - Dr S Hay fellowship

  Hay, S. (PI)

  1/09/10 → 31/08/15

  Project: Research

  • Kinetic Isotope Effect 100%
  • Electron Transport 81%
  • Dynamics 78%
  • Motion 73%
  • Pentaerythritol Tetranitrate 71%