Conversion of magnetic impulses into cellular responses by self-assembled nanoparticle-vesicle hydrogels

Felicity De Cogan, Andrew Booth, Julie E. Gough, Simon J. Webb

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Crosslinking vesicles with magnetic nanoparticles produced MNPVs, self-assembled "nanopills" that can be "unlocked" by an alternating magnetic field (AMF), releasing chemical messengers stored within the vesicles. When MNPVs are co-immobilized with cells in a hydrogel matrix, exposure to an AMF magnetic signal releases the chemical messengers, which then induce a cellular response. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
    Original languageEnglish
    Pages (from-to)12290-12293
    Number of pages3
    JournalAngewandte Chemie - International Edition
    Volume50
    Issue number51
    DOIs
    Publication statusPublished - 16 Dec 2011

    Keywords

    • biomaterials
    • magnetoresponsive materials
    • nanoparticles
    • self-assembly
    • vesicles

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