Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence

John Mclaughlin; Christian P. Selinger; Yu Kinjo; D. Brian Jones; Peter Katelaris; Grace Chapman; Charles McDonald; Simon Lal; John McLaughlin; Andrew Robinson; Rupert W L Leong

doi:10.1016/j.crohns.2012.11.006

Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence

John Mclaughlin, Christian P. Selinger, Yu Kinjo, D. Brian Jones, Peter Katelaris, Grace Chapman, Charles McDonald, Simon Lal, John McLaughlin, Andrew Robinson, Rupert W L Leong

Research output: Contribution to journal › Article › peer-review

Abstract

Background and aim: Adherence to medication that maintains remission by patients with ulcerative colitis (UC) is poor but little is known regarding patients' perception of medication benefit that may enhance adherence rates. The aims were to study patients' understanding and preference on methods of conveying statistical information and to study indicated thresholds for adherence to medication for UC. Methods: Four methods of displaying information on benefits of maintenance therapy were explained to patients with UC in remission: relative risk reduction [RR], absolute risk reduction [AR], number needed to treat [NNT] and optical representation via Cates plot [CP]. Patients' understanding and preference for each method were evaluated. Participants were asked to state minimum thresholds relating to relapse prevention and colorectal cancer risk reduction that they would require in order for them to adhere to medication for UC. Results: Of 50 participants, 48% preferred data presentation by RR over CP (28%), AR (20%) and NNT (4%). 94% found RR easy to understand, better than AR (88%), CP (74%), or NNT (48%). For bowel cancer prevention, 94% indicated adherence for benefit levels of 61% RR but only 57% for the corresponding CP (P

Original language	English
Pages (from-to)	e312-e317
Journal	Journal of Crohn's and Colitis
Volume	7
Issue number	8
DOIs	https://doi.org/10.1016/j.crohns.2012.11.006
Publication status	Published - 1 Sept 2013

Keywords

Adherence;
Communication
Medication benefits;
Ulcerative colitis;

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.crohns.2012.11.006

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Mclaughlin, J., Selinger, C. P., Kinjo, Y., Jones, D. B., Katelaris, P., Chapman, G., McDonald, C., Lal, S., McLaughlin, J., Robinson, A., & Leong, R. W. L. (2013). Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence. Journal of Crohn's and Colitis, 7(8), e312-e317. https://doi.org/10.1016/j.crohns.2012.11.006

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title = "Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence",

abstract = "Background and aim: Adherence to medication that maintains remission by patients with ulcerative colitis (UC) is poor but little is known regarding patients' perception of medication benefit that may enhance adherence rates. The aims were to study patients' understanding and preference on methods of conveying statistical information and to study indicated thresholds for adherence to medication for UC. Methods: Four methods of displaying information on benefits of maintenance therapy were explained to patients with UC in remission: relative risk reduction [RR], absolute risk reduction [AR], number needed to treat [NNT] and optical representation via Cates plot [CP]. Patients' understanding and preference for each method were evaluated. Participants were asked to state minimum thresholds relating to relapse prevention and colorectal cancer risk reduction that they would require in order for them to adhere to medication for UC. Results: Of 50 participants, 48% preferred data presentation by RR over CP (28%), AR (20%) and NNT (4%). 94% found RR easy to understand, better than AR (88%), CP (74%), or NNT (48%). For bowel cancer prevention, 94% indicated adherence for benefit levels of 61% RR but only 57% for the corresponding CP (P",

keywords = "Adherence;, Communication, Medication benefits;, Ulcerative colitis;",

author = "John Mclaughlin and Selinger, {Christian P.} and Yu Kinjo and Jones, {D. Brian} and Peter Katelaris and Grace Chapman and Charles McDonald and Simon Lal and John McLaughlin and Andrew Robinson and Leong, {Rupert W L}",

year = "2013",

month = sep,

day = "1",

doi = "10.1016/j.crohns.2012.11.006",

language = "English",

volume = "7",

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Mclaughlin, J, Selinger, CP, Kinjo, Y, Jones, DB, Katelaris, P, Chapman, G, McDonald, C, Lal, S, McLaughlin, J, Robinson, A & Leong, RWL 2013, 'Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence', Journal of Crohn's and Colitis, vol. 7, no. 8, pp. e312-e317. https://doi.org/10.1016/j.crohns.2012.11.006

TY - JOUR

T1 - Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence

AU - Mclaughlin, John

AU - Selinger, Christian P.

AU - Kinjo, Yu

AU - Jones, D. Brian

AU - Katelaris, Peter

AU - Chapman, Grace

AU - McDonald, Charles

AU - Lal, Simon

AU - McLaughlin, John

AU - Robinson, Andrew

AU - Leong, Rupert W L

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Background and aim: Adherence to medication that maintains remission by patients with ulcerative colitis (UC) is poor but little is known regarding patients' perception of medication benefit that may enhance adherence rates. The aims were to study patients' understanding and preference on methods of conveying statistical information and to study indicated thresholds for adherence to medication for UC. Methods: Four methods of displaying information on benefits of maintenance therapy were explained to patients with UC in remission: relative risk reduction [RR], absolute risk reduction [AR], number needed to treat [NNT] and optical representation via Cates plot [CP]. Patients' understanding and preference for each method were evaluated. Participants were asked to state minimum thresholds relating to relapse prevention and colorectal cancer risk reduction that they would require in order for them to adhere to medication for UC. Results: Of 50 participants, 48% preferred data presentation by RR over CP (28%), AR (20%) and NNT (4%). 94% found RR easy to understand, better than AR (88%), CP (74%), or NNT (48%). For bowel cancer prevention, 94% indicated adherence for benefit levels of 61% RR but only 57% for the corresponding CP (P

AB - Background and aim: Adherence to medication that maintains remission by patients with ulcerative colitis (UC) is poor but little is known regarding patients' perception of medication benefit that may enhance adherence rates. The aims were to study patients' understanding and preference on methods of conveying statistical information and to study indicated thresholds for adherence to medication for UC. Methods: Four methods of displaying information on benefits of maintenance therapy were explained to patients with UC in remission: relative risk reduction [RR], absolute risk reduction [AR], number needed to treat [NNT] and optical representation via Cates plot [CP]. Patients' understanding and preference for each method were evaluated. Participants were asked to state minimum thresholds relating to relapse prevention and colorectal cancer risk reduction that they would require in order for them to adhere to medication for UC. Results: Of 50 participants, 48% preferred data presentation by RR over CP (28%), AR (20%) and NNT (4%). 94% found RR easy to understand, better than AR (88%), CP (74%), or NNT (48%). For bowel cancer prevention, 94% indicated adherence for benefit levels of 61% RR but only 57% for the corresponding CP (P

KW - Adherence;

KW - Communication

KW - Medication benefits;

KW - Ulcerative colitis;

U2 - 10.1016/j.crohns.2012.11.006

DO - 10.1016/j.crohns.2012.11.006

M3 - Article

SN - 1873-9946

VL - 7

SP - e312-e317

JO - Journal of Crohn's and Colitis

JF - Journal of Crohn's and Colitis

IS - 8

ER -

Conveying medication benefits to ulcerative colitis patients and effects on patient attitudes regarding thresholds for adherence

Abstract

Keywords

UN SDGs

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