Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis

Akihide Yoshimi; Kuan-Ting Lin; Daniel Wiseman; Mohammad Rahman; Alessandro Pastore; Bo Wang; Stanley Lee; Jean-Baptiste Micol; Xiao Zhang; Stephane de Botton; Virginie Penard-Lacronique; Eytan Stein; Hana Cho; Rachel Miles; Daichi Inoue; Todd Albrecht; Tim Somervaille; Kiran Batta; Fabio Amaral; Fabrizio Simeoni; Deepti Wilks; Catherine Cargo; Andrew Intlekofer; Ross Levine; Heidi Dvinge; Robert Bradley; Eric Wagner; Adrian Krainer; Omar Abdel-Wahab

doi:10.1038/s41586-019-1618-0

Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis

Akihide Yoshimi (Lead), Kuan-Ting Lin (Lead), Daniel Wiseman (Lead), Mohammad Rahman, Alessandro Pastore, Bo Wang, Stanley Lee, Jean-Baptiste Micol, Xiao Zhang, Stephane de Botton, Virginie Penard-Lacronique, Eytan Stein, Hana Cho, Rachel Miles, Daichi Inoue, Todd Albrecht, Tim Somervaille, Kiran Batta, Fabio Amaral, Fabrizio SimeoniDeepti Wilks, Catherine Cargo, Andrew Intlekofer, Ross Levine, Heidi Dvinge, Robert Bradley, Eric Wagner, Adrian Krainer, Omar Abdel-Wahab (Corresponding)

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	273-277
Journal	Nature
Volume	574
DOIs	https://doi.org/10.1038/s41586-019-1618-0
Publication status	Published - 2 Oct 2019

Research Beacons, Institutes and Platforms

Manchester Cancer Research Centre

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/s41586-019-1618-0

Cite this

Yoshimi, A., Lin, K.-T., Wiseman, D., Rahman, M., Pastore, A., Wang, B., Lee, S., Micol, J.-B., Zhang, X., de Botton, S., Penard-Lacronique, V., Stein, E., Cho, H., Miles, R., Inoue, D., Albrecht, T., Somervaille, T., Batta, K., Amaral, F., ... Abdel-Wahab, O. (2019). Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis. Nature, 574, 273-277. https://doi.org/10.1038/s41586-019-1618-0

@article{b3c7b970f57c45e3b3ba42e6497a4b32,

title = "Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis",

author = "Akihide Yoshimi and Kuan-Ting Lin and Daniel Wiseman and Mohammad Rahman and Alessandro Pastore and Bo Wang and Stanley Lee and Jean-Baptiste Micol and Xiao Zhang and {de Botton}, Stephane and Virginie Penard-Lacronique and Eytan Stein and Hana Cho and Rachel Miles and Daichi Inoue and Todd Albrecht and Tim Somervaille and Kiran Batta and Fabio Amaral and Fabrizio Simeoni and Deepti Wilks and Catherine Cargo and Andrew Intlekofer and Ross Levine and Heidi Dvinge and Robert Bradley and Eric Wagner and Adrian Krainer and Omar Abdel-Wahab",

note = "Publication date scheduled for Oct 02, 2019 (doi provided in advance)",

year = "2019",

month = oct,

day = "2",

doi = "10.1038/s41586-019-1618-0",

language = "English",

volume = "574",

pages = "273--277",

journal = "Nature",

issn = "0028-0836",

publisher = "Springer Nature",

}

Yoshimi, A, Lin, K-T, Wiseman, D, Rahman, M, Pastore, A, Wang, B, Lee, S, Micol, J-B, Zhang, X, de Botton, S, Penard-Lacronique, V, Stein, E, Cho, H, Miles, R, Inoue, D, Albrecht, T, Somervaille, T , Batta, K, Amaral, F, Simeoni, F, Wilks, D, Cargo, C, Intlekofer, A, Levine, R, Dvinge, H, Bradley, R, Wagner, E, Krainer, A & Abdel-Wahab, O 2019, 'Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis', Nature, vol. 574, pp. 273-277. https://doi.org/10.1038/s41586-019-1618-0

TY - JOUR

T1 - Coordinated alterations in RNA splicing and epigenetic regulation drive leukemogenesis

AU - Rahman, Mohammad

AU - Pastore, Alessandro

AU - Wang, Bo

AU - Lee, Stanley

AU - Micol, Jean-Baptiste

AU - Zhang, Xiao

AU - de Botton, Stephane

AU - Penard-Lacronique, Virginie

AU - Stein, Eytan

AU - Cho, Hana

AU - Miles, Rachel

AU - Inoue, Daichi

AU - Albrecht, Todd

AU - Somervaille, Tim

AU - Batta, Kiran

AU - Amaral, Fabio

AU - Simeoni, Fabrizio

AU - Wilks, Deepti

AU - Cargo, Catherine

AU - Intlekofer, Andrew

AU - Levine, Ross

AU - Dvinge, Heidi

AU - Bradley, Robert

AU - Wagner, Eric

AU - Krainer, Adrian

A2 - Yoshimi, Akihide

A2 - Lin, Kuan-Ting

A2 - Wiseman, Daniel

A2 - Abdel-Wahab, Omar

N1 - Publication date scheduled for Oct 02, 2019 (doi provided in advance)

PY - 2019/10/2

Y1 - 2019/10/2

U2 - 10.1038/s41586-019-1618-0

DO - 10.1038/s41586-019-1618-0

M3 - Letter

SN - 0028-0836

VL - 574

SP - 273

EP - 277

JO - Nature

JF - Nature

ER -