COPD: Definition and phenotypes

Jorgen Vestbo; Jørgen Vestbo

doi:10.1016/j.ccm.2013.10.010

COPD: Definition and phenotypes

Jorgen Vestbo
, Jørgen Vestbo

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations. © 2014 Elsevier Inc.

Original language	English
Pages (from-to)	1-6
Number of pages	5
Journal	Clinics in Chest Medicine
Volume	35
Issue number	1
DOIs	https://doi.org/10.1016/j.ccm.2013.10.010
Publication status	Published - Mar 2014

Keywords

Chronic inflammation
COPD
Definition
Diagnosis
Lung function

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10.1016/j.ccm.2013.10.010

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AB - Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations. © 2014 Elsevier Inc.

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KW - COPD

KW - Definition

KW - Diagnosis

KW - Lung function

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COPD: Definition and phenotypes

Abstract

Keywords

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