Corneal biomechanical properties measured with the Ocular Response Analyser in a myopic population

Athina Plakitsi, Clare O'Donnell, Marco A Miranda, W. Neil Charman, Hema Radhakrishnan

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    Purpose: To explore the possible association between myopia and corneal biomechanical properties in a Caucasian population, and the correlations between the properties of right and left eyes. Methods: Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured using the Ocular Response Analyser (ORA) in both eyes of 95 normal adult subjects aged between 19 and 48years. The spherical equivalent refractive errors of the participants ranged from 0.25 to -14.00D. The mean CH and CRF values for the right and left eyes were recorded for each subject. CH and CRF data were compared between different refractive groups. Results: CH was found to be slightly lower in high myopes (>-6.00D, mean CH 10.0±1.2mmHg) in comparison to moderate myopes (>-3.00 to -6.00 D, 10.1±1.4mmHg) and emmetropes and low myopes (+0.25 to -2.75D, 10.9±1.5mmHg). The decrease in CH with the degree of myopia was about 0.13mmHg per D or roughly 1% per D (r2=0.084, p
    Original languageEnglish
    Pages (from-to)404-412
    Number of pages8
    JournalOphthalmic and Physiological Optics
    Issue number4
    Publication statusPublished - Jul 2011


    • Corneal biomechanics
    • Corneal hysteresis
    • Corneal resistance factor
    • Corneal thickness
    • Intraocular pressure
    • Ocular response analyser


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