Correspondence between retinal reflectometry and a flicker-based technique in the measurement of macular pigment spatial profiles

Rob L P Van Der Veen, Tos T J M Berendschot, Maria Makridaki, Fred Hendrikse, David Carden, Ian J. Murray

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A comparison of macular pigment optical density (MPOD) spatial profiles determined by an optical and a psychophysical technique is presented. We measured the right eyes of 19 healthy individuals, using fundus reflectometry at 0, 1, 2, 4, 6, and 8 deg eccentricity; and heterochromatic flicker photometry (HFP) at 0, 0.5, 1, 2, 3, 4, 5, 6, and 7 deg, and a reference point at 8 deg eccentricity. We found a strong correlation between the two techniques. However, the absolute estimates obtained by fundus reflectometry data were higher than by HFP. These differences could partly be explained by the fact that at 8 deg eccentricity the MPOD is not zero, as assumed in HFP. Furthermore, when performing HFP for eccentricities of
    Original languageEnglish
    Article number064046
    JournalJournal of Biomedical Optics
    Volume14
    Issue number6
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Fundus reflectometry
    • Heterochromatic flicker photometry
    • Macular pigment
    • Scanning laser ophthalmoscopy

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