COVID-19 in children with haematological malignancies

Gerard Cathal Millen, Roland Arnold, Jean-Baptiste Cazier, Helen Curley, Richard Feltbower, Ashley Gamble, Adam Glaser, Richard G Grundy, Laura Kirton, Lennard Y W Lee, Martin G McCabe, Claire Palles, Bob Phillips, Charles A Stiller, Csilla Varnai, Pamela Kearns

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.

METHODS: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.

RESULTS: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.

INTERPRETATION: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.

Original languageEnglish
Pages (from-to)186-188
Number of pages3
JournalArchives of Disease in Childhood
Issue number2
Early online date22 Jul 2021
Publication statusPublished - 1 Feb 2022


  • Adolescent
  • COVID-19/diagnosis
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Hematologic Neoplasms/epidemiology
  • Humans
  • Infant
  • Male
  • Risk Assessment/statistics & numerical data
  • Risk Factors
  • SARS-CoV-2/immunology
  • Severity of Illness Index

Research Beacons, Institutes and Platforms

  • Manchester Cancer Research Centre


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