Customised aberration-controlling corrections for keratoconic patients using contact lenses

Technological advancements in the design of soft and scleral contact lenses have led to the development of customised, aberration-controlling corrections for patients with keratoconus. As the number of contact lens manufacturers producing wavefront-guided corrections continues to expand, clinical interest in this customisable technology is also increasing among both patients and practitioners. This review outlines key issues surround- ing the measurement of ocular aberrations for patients with keratoconus, with a particular focus on the possible factors affecting the repeatability of Hartmann-Shack aberrometry measurements. This review also discusses and compares the relative successes of studies investigating the design and fitting of soft and scleral customised contact lenses for patients with keratoconus. A series of key limitations that should be considered before designing customised contact lens corrections is also described. Despite the challenges of producing and fitting customised lenses, improvements in visual performance and comfortable wear- ing times, as provided by these lenses, could help to reduce the rate of keratoplasty in keratoconic patients, thereby significantly reducing clinical issues related to corneal graft surgery. Furthermore, enhancements in optical correction, provided by customised lenses, could lead to increased independence, particularly among young adult keratoconic patients, therefore leading to improvements in quality of life.