Cyclin I is expressed in human breast cancer and closely associated with VEGF and KDR expression

  • Göran Landberg
  • , Kristina Nilsson
  • , Karin Jirström
  • , Lisa Rydén
  • , Richard Kitching
  • , Angelika M. Burger
  • , Arun Seth

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In the present study, cyclin I protein expression in 114 invasive human breast cancers was correlated with cell cycle and angiogenesis-related proteins and clinico-pathological data. A strong association was found between cytoplasmic cyclin I staining and VEGF (p = 0.001) as well as the VEGF receptor KDR (p = 0.001), suggesting a link between cyclin I and angiogenesis. © Springer 2005.
    Original languageEnglish
    Pages (from-to)313-316
    Number of pages3
    JournalBreast Cancer Research and Treatment
    Volume89
    Issue number3
    DOIs
    Publication statusPublished - Feb 2005

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Breast cancer
    • Cyclin I
    • Proliferation
    • VEGF

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